Chemical Formula: C22H19N7O
Exact Mass: 397.16511
Molecular Weight: 397.43
Elemental Analysis: C, 66.49; H, 4.82; N, 24.67; O, 4.03
Description: IC-87114 is a potent and ATP-competitive PI3K p110δ isoform-selective inhibitor (IC50 = 60 nM). It Inhibits p110α, p110β and p110γ only at much higher concentrations. It does not inhibit other PIK-related kinases such as ATM, ATR, DNA-PK, and mTOR even at concentrations up to 100 ÂµM.