Amuvatinib(MP470 )

Name MP 470 Synonyms N-(1,3-Benzodioxol-5-ylmethyl)-4-benzofuro[3,2-d]pyrimidin-4-yl-1-piperazinecarbothioamide Molecular Structure Molecular Formula C23H21N5O3S Molecular Weight 447.51 CAS Registry Number 850879-09-3

XL765(SAR245409)

Catalog No:LP000274 Product Name:MP470 CAS No:1349796-36-6 Purity: ≥99% Solubility: In DMSO Storage: -10°C Phosphatidylinositol 3-kinase (PI3K) and the mammalian target of rapamycin (Item No. 13346) (mTOR) constitutively signal and drive cell survival and proliferation in many forms of cancer.1,2 XL765 is a dual inhibitor of both PI3K and mTOR, completely blocking phosphorylation of substrates at…