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XL765(SAR245409)

Feb 25, 2018adminActive small molecule, Products1349796-36-6, MP470

Catalog No:LP000274 Product Name:MP470 CAS No:1349796-36-6 Purity: ≥99% Solubility: In DMSO Storage: -10°C Phosphatidylinositol 3-kinase (PI3K) and the mammalian target of rapamycin (Item No. 13346) (mTOR) constitutively signal and drive cell survival and proliferation in many forms of cancer.1,2 XL765 is a dual inhibitor of both PI3K and mTOR, completely blocking phosphorylation of substrates at […]

ENMD-2076

Cat No:LP000273 Product Name:ENMD2076 CAS No:934353-76-1 Purity: ≥99% Solubility: In DMSO Storage: -10°C ENMD-2076 is a multi-kinase inhibitor that inhibits FMS-related tyrosine kinase 3 (FLT3), RET, and Aurora A kinase with IC50 values of 1.86, 10.4, and 14 nM, respectively.1 It inhibits additional kinases involved in angiogenesis such as VEGFR3, PDGFRα, and FGFR2, among others, […]