HA-1077

Active small molecule, Products, ,

Cat No:LP000106 Product Name:HA-1077;Fasudil hydrochloride CAS NO:105628-07-7 Purity: ≥99% Solubility: In DMSO Storage: -10°C Rho-associated kinase (ROCK), an effector of the small GTP-binding protein Rho, plays an important role in various cellular functions including vascular smooth muscle contraction, proliferation, and migration as well as inflammatory cell mobility.1 HA-1077 is a potent inhibitor of ROCK-II and […]

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Roflumilast

Active small molecule, Products, , , ,

Cat No:LP000105 Product Name:Roflumilast;B 9302-107;BY 217;BY 217;Daxas CAS NO:162401-32-3 Purity: ≥99% Solubility: In DMSO Storage: -10°C Type 4 cyclic nucleotide phosphodiesterase (PDE4) isoforms selectively inactivate the second messenger cAMP by hydrolyzing the phosphodiester bond, producing AMP.1 Roflumilast is a potent, cell-permeable inhibitor of PDE4 (IC50 = < 1 nM for both human PDE4B and PDE4D).2 […]

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