Cat No:LP000002 Product Name: SB 216763 ; Chem Name:3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione; CAS: 280744-09-4 Purity:99%+ In Stock SB-216763 (10-20 µM) induces β-catenin mediated-transcription in a dose-dependent manner in HEK293 cells. SB-216763 (10, 15 and 20 µM) can maintain mESCs with a pluripotent-like morphology in long-term culture. SB-216763 (10 µM) can maintain J1 mESCs in a pluripotent state for […]


Cat No:LP000001 Product Name:OTSSP167 CAS:1431697-89-0 Formula:C25H28Cl2N4O2 Purity:99%+ Maternal embryonic leucine zipper kinase (MELK) is a serine/threonine kinase that regulates signaling central to cell cycling, stem cell renewal, apoptosis, and other cellular processes.1 MELK is overexpressed in some forms of cancer, particularly those with aggressive undifferentiated tumors.2,3,4 OTSSP167 is a potent inhibitor of MELK (IC50 = […]