HA-1077 – LookPharma

Fasudil

Jul 6, 2018adminActive small molecule, Products103745-39-7, AT877, Fasudil, HA-1077

Cat No:LP000395 Product Name:Fasudil;HA-1077; AT877 CAS#103745-39-7 Fasudil has vasodilatory action and occupies the adenine pocket of the ATP-binding site of the enzyme[1]. Fasudil produces a competitive inhibition of the Ca2+-induced contraction of the depolarized rabbit aorta. Fasudil inhibits contractile responses to KCl, phenylephnne (PHE) and prostaglandin (PG) F2a[2]. Fasudil also exhibits vasodilator actions by inhibition […]

HA-1077

Cat No:LP000106 Product Name:HA-1077;Fasudil hydrochloride CAS NO:105628-07-7 Purity: ≥99% Solubility: In DMSO Storage: -10°C Rho-associated kinase (ROCK), an effector of the small GTP-binding protein Rho, plays an important role in various cellular functions including vascular smooth muscle contraction, proliferation, and migration as well as inflammatory cell mobility.1 HA-1077 is a potent inhibitor of ROCK-II and […]