Active small molecule – Page 245

DAPT（GSI-IX）

Sep 5, 2018adminActive small molecule208255-80-5, DAPT, GSI-IX

Name: DAPT CAS#: 208255-80-5 Chemical Formula: C23H26F2N2O4 Exact Mass: 432.1861 Molecular Weight: 432.4678 Elemental Analysis: C, 63.88; H, 6.06; F, 8.79; N, 6.48; O, 14.80 Description: DAPT, also known GSI-IX, is a potent and selective γ-secretase inhibitor. DAPT is a non-transition-state analogue GSI and is the compound most widely evaluated in experimental models. DAPT causes […]

CUDC-907

Sep 5, 2018adminActive small molecule1339928-25-4, CUDC-907

Name: Fimepinostat CAS#: 1339928-25-4 Chemical Formula: C23H24N8O4S Exact Mass: 508.16412 Molecular Weight: 508.55 Elemental Analysis: C, 54.32; H, 4.76; N, 22.03; O, 12.58; S, 6.31 Description: CUDC-907, also known as fimepinostat, is an orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon […]