RGFP 966

Name: Axon 2195 CAS# 1357389-11-7 MF: C21H19FN4O MW: 362.40 Purity:99% Soluble in DMSO Description:HDAC3 specific inhibitor (IC50 value 0.08 μM) lacking affinity for any other HDAC at concentrations up to 15 μM. RGFP 966 enhances long term object memory acquisition/consolidation, and facilitates extinction of cocaine-seeking behavior in male C57BL/6J mice.


Cat No:LP000267 Product Name:RGFP966 CAS No:1357389-11-7 Purity: ≥99% Solubility: In DMSO Storage: -10°C RGFP966 potently and selectively inhibits HDAC 3 with IC50 of 0.21 μM in RAW 264.7 macrophages, while HDACs 1 (IC50=5.6 μM), 2 (9.7 μM) and 8 (>100 μM), indicating a good level of selectivity for HDAC 3. The mRNA levels of HDACs […]