GS-9973
Cat No:LP000387 Product Name:GS-9973;Entospletinib CAS#1229208-44-9 GS-9973 shows good bidirectional permeability across Caco-2 cell monolayers in vitro. In cells, GS-9973 also shows excellent selectivity for Syk, and potently inhibits BCR-mediated activation and proliferation of B-cells as well as immune-complex-stimulated cytokine production in monocytes[1]. The combination of idelalisib and GS-9973 synergistically inhibits CLL cell viability and further […]