Name Decernotinib Synonyms (2R)-2-Methyl-2-[[2-(1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]-N-(2,2,2-trifluoroethyl)butanamide; VRT 831509; VX 509 Molecular Structure Molecular Formula C18H19F3N6O Molecular Weight 392.38 CAS Registry Number 944842-54-0
Cat No:LP000410 Product Name:VX-509;Decernotinib;VRT-831509 CAS#944842-54-0 VX-509 is a selective inhibitor of Janus kinase 3 (JAK3) with a Ki value of 2.5 nM in enzyme assays and an IC50 value of 50-170 nM in cellular assays dependent on JAK3 activity with no measurable activity against other JAK isotypes.1 At 10-100 mg/kg, it has been shown to […]