Alpelisib
Cat No:LP000034 CAS NO: 1217486-61-7 Molecular Formula: C19H22F3N5O2S Molecular Weight: 441.47 Purity: 98% min Solubility: In DMSO Storage: -20°C BYL-719 (NVP-BYL719) potently inhibits the 2 most common PIK3CA somatic mutations (H1047R, E545K; IC50~4 nM). BYL-719 potently inhibits Akt phosphorylation in cells transformed with PI3Kα (IC50=74±15 nM) and shows significant reduced inhibitory activity in PI3Kβ or […]