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SR9243

Jul 17, 2018adminActive small molecule, Products1613028-81-1, SR9243

Cat No:LP000418 Product Name:SR9243 CAS#1613028-81-1 SR9243 specifically targets LXR and downregulates LXR-mediated gene expression, dose-dependently suppresses LXRα- and LXRβ-dependent transcription at nanomolar concentrations, and potently inhibits LXR-driven luciferase activity in cultured cancer cells. SR9243 potently reduces cancer cell viability at nanomolar concentrations (IC50 appr 15-104 nM) in prostate (PC3 and!DU-145), colorectal (SW620 and HT29), and […]

IKK-16

Cat No:LP000417 Product Name:IKK-16 CAS#1186195-62-9 IKK-16 is a potent inhibitor of IκB kinases (IKKs), displaying IC50 values of 200, 40, and 70 nM for IKKα, IKKβ, and IKK complex, respectively, in cell-free assays.1 It is effective in cells and in animals and has been used delineate the role of NF-κB signaling in diverse contexts.2,3,4,5 IKK-16 […]