Cat No:LP000417
Product Name:IKK-16
CAS#1186195-62-9
IKK-16 is a potent inhibitor of IκB kinases (IKKs), displaying IC50 values of 200, 40, and 70 nM for IKKα, IKKβ, and IKK complex, respectively, in cell-free assays.1 It is effective in cells and in animals and has been used delineate the role of NF-κB signaling in diverse contexts.2,3,4,5 IKK-16 has also been reported to inhibit protein kinase D isoforms and the ATP-binding cassette (ABC) transporter ABCB1.6,7.
