| CAS No. | 2055536-64-4 | Cat. No. | BCP28882 |
| Related Products | 2055538-47-9（Cintirorgon sodium） | ||
| Name | Cintirorgon | ||
| Synonyms | LYC 55716;LYC55716; LYC-55716; | ||
| SMILES | O=C(O)C(C)(C)C[C@H]1CN(S(=O)(C2=CC=CC(C(F)(F)F)=C2)=O)C3=CC(C4=CC(F)=CC(OC(F)F)=C4)=CC=C3O1 | ||
| Chemical Name |  |
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| Formula | C27H23F6NO6S | M. Wt | 603.53 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Cintirorgon, also known as LYC-55716, is a potent and orally active RORgamma agonist with potential immunomodulatory and antineoplastic activities. LYC-55716 selectively binds to the nuclear receptor transcription factor RORg, forming a receptor complex that translocates to the nucleus, and binds to ROR response elements (ROREs), enhancing the function, proliferation and survival of type 17 T cells, including Th17 (helper T cells) and Tc17 (cytotoxic T cells). | ||
