Products – Page 727

GZD824

Aug 18, 2017adminActive small molecule, Products1257628-77-5, GZD824

Cat No:LP000028 Product Name:GZD824,GZD-824 CAS:1257628-77-5 Purity:99%+ In Stock GZD824 is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I) with IC50 of 0.34 nM and 0.68 nM, respectively. IC50 Value: 0.34/0.68 nM(Bce-Abl wt/T315I) [1] Target: Bcr-Abl in vitro: GZD824 potently suppressed proliferation of Bcr-Abl-positive K562 and Ku812 human CML cells with IC(50) values of […]

LY2835219

Cat No:LP000027 Product Name:LY2835219,ABEMACICLIB CAS:1231930-82-7 Purity:99%+ In Stock LY2835219 reduces cell viability with the IC50 values ranging from 0.5 μM to 0.7 μM, inhibits Akt and ERK signaling but not mTOR activation at head and neck squamous cell carcinoma (HNSCC) cells[1]. LY2835219 shows inhibition on A375R1-4, M14R, and SH4R with EC50 values ranging from 0.3 […]