Products – Page 716

Olaparib

Feb 19, 2018adminActive small molecule, Products763113-22-0, AZD2281, Olaparib

Cat No:LP000050 Product Name:Olaparib;AZD2281 CAS NO: 763113-22-0 Molecular Formula: C24H23FN4O3 Molecular Weight: 434.46300 Purity:≥98% Solubility:In DMSO Storage:-10°C Olaparib (AZD2281) is a single digit nanomolar inhibitor of both PARP-1 and PARP-2 that shows standalone activity against BRCA1-deficient breast cancer cell lines. Olaparib is applied to SW620 cell lysates, and identified the IC50 for PARP-1 inhibition to […]

Veliparib

Cat No:LP000049 Product Name:Veliparib;ABT-888 CAS NO:912444-00-9 Molecular Formula:C13H16N4O Molecular Weight: 244.29200 Purity:≥98% Solubility:In DMSO Storage:-10°C Veliparib (ABT-888) is also tested against SIRT2, an enzyme that also uses NAD+ for catalysis, and found to be inactive (>5,000 nM). The receptor profile of Veliparib is determined in a panel of 74 receptor-binding assays at a concentration of […]