AZD6244

Active small molecule, Products,

Cat No:LP000066 Product Name:AZD6244;ARRY-142886;CL 1,040;NSC 741O78;Selumetinib CAS NO:606143-52-6 Purity: ≥99% Solubility: In DMSO Storage: -10°C MEK kinases are central components of diverse intracellular signaling pathways. MEK1 and MEK2 specifically act downstream of growth factor receptors and the proto-oncogenes Ras and Raf to activate ERK1 and ERK2, often leading to an increase in cell proliferation.1 AZD […]

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Rucaparib

Active small molecule, Products, ,

Cat No:LP000065 Product Name:AG014699 CAS NO:459868-92-9 Purity: ≥99% Solubility: In DMSO Storage: -10°C Poly(ADP-ribose) polymerases (PARPs) are activated by DNA single- and double-strand breaks and promote repair of DNA damage through the relaxation of chromatin and recruitment of other repair proteins.1,2,3 Inhibition of PARP activity has been linked to synthetic lethality in cells with mutations […]

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