Cat No:LP000070 Product Name:MLN8237 CAS NO:1028486-01-2 Purity: ≥99% Solubility: In DMSO Storage: -10°C MLN8237 is a selective inhibitor of Aurora A kinase (IC50s = 1 and 1,100 nM for Aurora A and B, respectively).1,2,3 At 20 mg/kg it inhibits tumor growth in nude mice bearing Calu-6 human lung tumor xenografts.1 MLN8237 has been evaluated for […]
Cat No:LP000069 Product Name:A-674563(HCL) CAS NO:552325-73-2 Purity: ≥99% Solubility: In DMSO Storage: -10°C Three related forms of the kinase Akt (1, 2, 3, also known as protein kinase B isoforms PKBα, β, γ) modulate cell proliferation, metabolism, and survival, as well as angiogenesis. A-674563 is an orally available, ATP-competitive, and reversible inhibitor of Akt (Ki […]