Products – Page 699

PI-103

Feb 22, 2018adminActive small molecule, Products371935-74-9, PI-103

Cat No:LP000084 Product Name:PI-103 CAS NO:371935-74-9 Purity: ≥99% Solubility: In DMSO Storage: -10°C The phosphatidylinositol 3-kinases (PI3K) family of enzymes is comprised of 15 members that are divided into 3 classes according to their structure, substrate specificity, and mode of regulation.1,2 PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of phosphatidylinositol 3-kinase (PI3K) family members with […]

MS-275

Cat No:LP000083 Product Name:ms-275;Entinostat;SNDX 275 CAS NO:209783-80-2 Purity: ≥99% Solubility: In DMSO Storage: -10°C MS-275 is an inhibitor of histone deacetylases (HDACs) that preferentially inhibits HDAC1 (IC50 = 300 nM) over HDAC3 (IC50 = 8 μM).1 However, it does not inhibit HDAC8 (IC50 > 100 μM).1 MS-275 induces cyclin-dependent kinase inhibitor 1A (p21/CIP1/WAF1), slowing cell […]