Products – Page 691

SNS-032

Cat No:LP000100 Product Name:sns-032;BMS-387032 CAS NO:345627-80-7 Purity: ≥99% Solubility: In DMSO Storage: -10°C SNS-032 has low sensitivity to CDK1 and CDK4 with IC50 of 480 nM and 925 nM, respectively. SNS-032 effectively kills chronic lymphocytic leukemia cells in vitro regardless of prognostic indicators and treatment history. Compared with flavopiridol and roscovitine, SNS-032 is more potent, […]

PLX4032

Feb 22, 2018adminActive small molecule, Products1029872-54-5, PLX-4032, RG-7204, Vemurafenib

Cat No:LP000099 Product Name:PLX4032;RG-7204;Ro 51-85426;Vemurafenib CAS NO:1029872-54-5 Purity: ≥99% Solubility: In DMSO Storage: -10°C PLX4032 is an orally bioavailable, ATP-competitive inhibitor of mutant V600E and wild type B-Raf kinases (IC50s = 31 and 100 nM, respectively).1 It inhibits cell proliferation in a variety of cell lines expressing B-Raf V600E and synergizes strongly with taxol, vinblastine, […]