Products – Page 682

RAF265

Feb 23, 2018adminActive small molecule, Products927880-90-8, CHIR-265, RAF265

Cat No:LP000118 Product Name:RAF265;CHIR-265 CAS No:927880-90-8 Purity: ≥99% Solubility: In DMSO Storage: -10°C RAF265 (CHIR-265) is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM, and exhibits potent inhibition on VEGFR2 phosphorylation with EC50 of 30 nM. IC50 value: 3-60 nM (B-Raf); 30 nM(EC50 for VEGFR2) [1] Target: B-Raf; VEGFR2; B-Raf V600E […]

LY2109761

Feb 23, 2018adminActive small molecule, Products700874-71-1, LY2109761

Cat No:LP000117 Product Name:LY2109761 CAS No:700874-71-1 Purity: ≥99% Solubility: In DMSO Storage: -10°C LY2109761 significantly inhibits the growth of L3.6pl/GLT soft agar colonies in a dose-dependent manner, and results in appr 33% inhibition at 2 μM and 73% inhibition at 20 μM. Targeting TβRI/II kinase activity with LY2109761 (5 μM) almost completely suppresses both the […]