Active small molecule – Page 257

Zosuquidar trihydrochloride

Sep 5, 2018adminActive small molecule167465-36-3, LY335979, Zosuquidar, Zosuquidar trihydrochloride

Name: Zosuquidar trihydrochloride CAS#: 167465-36-3 ( HCl) Chemical Formula: C32H34Cl3F2N3O2 Exact Mass: Molecular Weight: 637.0 Elemental Analysis: C, 60.34; H, 5.38; Cl, 16.70; F, 5.97; N, 6.60; O, 5.02 Description: Zosuquidar, also known as LY-335979, is a potent P-glycoprotein (P-gp) inhibitor, which binds with high affinity to P-glycoprotein and inhibits P-glycoprotein-mediated multidrug resistance (MDR). […]

Luminespib (AUY-922 )

Name: Luminespib (AUY-922 ) CAS#: 747412-49-3 Chemical Formula: C26H31N3O5 Exact Mass: 465.22637 Molecular Weight: 465.54 Elemental Analysis: C, 67.08; H, 6.71; N, 9.03; O, 17.18 Description: Luminespib, also known as AUY-922 (or NVP-AUY922), is a derivative of 4,5-diarylisoxazole and a third-generation heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor AUY922 […]