Active small molecule – Page 251

AR-A014418

Name: AR-A014418 CAS#: 487021-52-3 Chemical Formula: C12H12N4O4S Exact Mass: 308.05793 Molecular Weight: 308.31 Elemental Analysis: C, 46.75; H, 3.92; N, 18.17; O, 20.76; S, 10.40 Description: AR-A014418 , also known as SN 4521, is a labeled Glycogen Synthase Kinase 3β (GSK-3β) inhibitor. AR-A014418 suppresses pancreatic cancer cell growth via inhibition of GSK-3-mediated Notch1 expression. […]

Apremilast（CC-10004）

Sep 5, 2018adminActive small molecule608141-41-9, Apremilast, CC-10004

Name: Apremilast CAS#: 608141-41-9 Chemical Formula: C22H24N2O7S Exact Mass: 460.13042 Molecular Weight: 460.5 Elemental Analysis: C, 57.38; H, 5.25; N, 6.08; O, 24.32; S, 6.96 Description: Apremilast, also known as CC-10004, is a thalidomide analog and is an orally available small molecule inhibitor of phosphodiesterase 4 (PDE4). Apremilast specifically inhibits PDE4 and inhibits spontaneous […]