Active small molecule – Page 244

Roxadustat（FG-4592）

Sep 5, 2018adminActive small molecule808118-40-3, FG-4592, Roxadustat

Name: Roxadustat CAS#: 808118-40-3 Chemical Formula: C19H16N2O5 Exact Mass: 352.10592 Molecular Weight: 352.35 Elemental Analysis: C, 64.77; H, 4.58; N, 7.95; O, 22.70 Description: Roxadustat, also known as ASP1517 and FG-4592, is an HIF α prolyl hydroxylase inhibitor in a cell-free assay. It stabilizes HIF-2 and induces EPO production and stimulates erythropoiesis. Roxadustat transiently and […]

EX-52

Name: Selisistat CAS#: 49843-98-3 Chemical Formula: C13H13ClN2O Exact Mass: 248.0716 Molecular Weight: 248.71 Elemental Analysis: C, 62.78; H, 5.27; Cl, 14.25; N, 11.26; O, 6.43 Description: Selisistat, also known as EX-527, is a SirT1 inhibitor for treatment of Huntington’s disease. EX-527 inhibits Sirtuins by exploiting their unique NAD+-dependent deacetylation mechanism. Galectin-9 in Combination With […]