Apatinib free base

Name: Apatinib free base
CAS#: 811803-05-1 (free base)
Chemical Formula: C24H23N5O
Exact Mass: 397.1903
Molecular Weight: 397.482
Elemental Analysis: C, 72.52; H, 5.83; N, 17.62; O, 4.03
Description: Apatinib, also known as Rivoceranib, is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. The free-base form is also known as Rivoceranib. Apatinib selectively binds to and inhibits vascular endothelial growth factor receptor 2, which may inhibit VEGF-stimulated endothelial cell migration and proliferation and decrease tumor microvessel density. In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases.

Leave a Reply

Your email address will not be published. Required fields are marked *