Chemical Formula: C27H35N5
Exact Mass: 429.28925
Molecular Weight: 429.6
Elemental Analysis: C, 75.49; H, 8.21; N, 16.30
Description: GANT61 is a small-molecule inhibitor of glioma-associated oncogene 1 (GLI1)- and GLI2-mediated transcription at the nuclear level that exerts its effect by preventing DNA binding. It has been demonstrated to induce cell death against Ewing’s sarcoma family tumor (ESFT) cell lines in a dose-dependent manner.