Cat No:LP000317
Product Name:XY1
CAS#1624117-53-8
Molecular Formula:C17H19N3O2
Molecular Weight:297.35
Protein arginine N-methyltransferase 3 (PRMT3, Item No. 11642) is a predominantly cytoplasmic enzyme that is constitutively expressed.1,2 SGC707 (Item No. 17017) is a potent, selective allosteric inhibitor of PRMT3 (IC50 = 50 nM). It inhibits the methylation of histones in cells with an IC50 value below 1 µM. XY1 is a close analog of SGC707 that is completely inactive against PRMT3 at concentrations as high as 100 µM.3 It is intended to be used as a negative control for SGC707 in studies involving PRMT3 action. See the Structural Genomics Consortium (SGC) website for more information.
