SB-525334
Cat No:LP000293 Product Name:SB 525334 CAS No:356559-20-1 Purity:≥99% Solubility: In DMSO Storage:at -20°C 2 years SB-525334 is a potent inhibitor of the TGF-β receptor 1 (TGF-β R1, ALK5) kinase (IC50 = 14.36 nM).1 It is ~4-fold less effective against ALK4 and inactive against ALK2, ALK3, and ALK6.1 SB-525334 blocks TGF-β1-induced phosphorylation and nuclear translocation of […]