LY-364947(HTS466284)

Cat No:LP000176 Product Name:LY-364947;HTS466284 CAS No:396129-53-6 Purity: ≥99% Solubility: In DMSO Storage: -10°C LY-364947 is an ATP competitive and tight-binding inhibitor, inhibiting phosphorylation of P-Smad3 by TGFβR-I Kinase with Ki of 28 nM. LY-364947 inhibits in vivo Smad2 phosphorylation within the NMuMg cells with IC50 of 135 nM. LY-364947 reverses TGF-β-mediated growth inhibition in NMuMg […]