Roflumilast
Cat No:LP000105 Product Name:Roflumilast;B 9302-107;BY 217;BY 217;Daxas CAS NO:162401-32-3 Purity: ≥99% Solubility: In DMSO Storage: -10°C Type 4 cyclic nucleotide phosphodiesterase (PDE4) isoforms selectively inactivate the second messenger cAMP by hydrolyzing the phosphodiester bond, producing AMP.1 Roflumilast is a potent, cell-permeable inhibitor of PDE4 (IC50 = < 1 nM for both human PDE4B and PDE4D).2 […]