VX809
Cat No:LP000219 Product Name:vx809 CAS No:936727-05-8 Purity: ≥99% Solubility: In DMSO Storage: -10°C In fischer rat thyroid (FRT) cells, VX-809 improves F508del-CFTR maturation by 7.1±0.3 fold (n=3) compared with vehicle-treated cells (EC50, 0.1±0.1 μM; n=3) and enhances F508del-CFTR-mediated chloride transport by approximately fivefold (EC50, 0.5±0.1 μM; n=3). At VX-809 concentrations greater than 10 μM, the […]