GW 501516

Cat No:LP000302 Product Name:GW 501516 Synonyms:2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid CAS#317318-70-0 Molecular Formula:C21H18F3NO3S2 Molecular Weight:453.50 GW 501516 is shown to be the most potent and selective PPARα agonists known with an EC50 of 1.1 nM against PPARα and 1000-fold selectivity over the other human subtypes, PPARα and-γ[1]. GW 501516 exerts anti-inflammatory effects in mouse cultured proximal tubular (mProx) […]