Acalabrutinib
Cat No:LP000353 Product Name:Acalabrutinib;ACP-196 CAS#1420477-60-6 Molecular Formula:C26H23N7O2 Molecular Weight:465.51 In the human CLL NSG xenograft model, acalabrutinib demonstrates on-target effects including decreased phosphorylation of PLCγ2, ERK and significant inhibition of CLL cell proliferation. Acalabrutinib significantly decreases tumor burden in the spleen of the mice. In the TCL1 adoptive transfer model, acalabrutinib treatment decreases phosphorylation of […]