EPZ-6438
Cat No:LP000402 Product Name:EPZ-6438;Tazemetostat;E-7438 CAS#1403254-99-8 EPZ-6438 inhibits EZH2 in a manner competitive with the substrate S-adenosylmethionine (SAM). EPZ-6438 inhibits EZH1, EZH2(in peptide assay), EZH2 (in nucleosome assay) with IC50of 392 nM, 11 nM and 16 nM, respectively. EPZ-6438 displays a 35-fold selectivity versus EZH1 and >4,500-fold selectivity relative to 14 other HMTs tested[1]. EPZ-6438 (125 […]