CO-1686

Cat No:LP000266 Product Name:CO1686 CAS No:1374640-70-6 Purity: ≥99% Solubility: In DMSO Storage: -10°C CO-1686 (0.1 μM) inhibits EGFR potently and irreversibly, and inhibits more than 50% of 23 targets. CO-1686 potently and selectively inhibits growth of NSCLC cells expressing mutant EGFR and induces apoptosis. CO-1686 resistant NSCLC cell lines are sensitive to AKT inhibition.