GSK503
Cat No:LP000406 Product Name:GSK503 CAS#1346572-63-1 GSK503 inhibits the methyltransferase activity of wild type and mutant EZH2 with similar potency (Kiapp=3-27 nM) and is structurally related to GSK126 and GSK343. GSK503 is >200 fold selective over EZH1 (Kiapp=636 nM) and >4000 fold selective over other histone methyltransferases[1]. In a melanoma mouse model, conditional EZH2 ablation as […]