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CX-4945

Feb 23, 2018adminActive small molecule, Products1009820-21-6, CX-4945, Silmitasertib

Cat No:LP000116 Product Name:CX-4945;Silmitasertib CAS No:1009820-21-6 Purity: ≥99% Solubility: In DMSO Storage: -10°C CX-4945 causes cell-cycle arrest and selectively induces apoptosis in cancer cells relative to normal cells, attenuates PI3K/Akt signalingand, and the antiproliferative activity of CX-4945 is correlated with expression levels of the CK2α catalytic subunit, Attenuation of PI3K/Akt signaling[1]. CX-4945 with bortezomib treatment […]

AZD-5438

Cat No:LP000115 Product Name:AZD5438 CAS NO:602306-29-6 Purity: ≥99% Solubility: In DMSO Storage: -10°C AZD5438 potently inhibits the kinase activity of cyclin E-cdk2, cyclin A-cdk2, cyclin B1-cdk1, p25-cdk5, cyclin D3-cdk6, and cyclin T-cdk9 (IC50, 6, 45, 16, 21, and 20 nM, respectively). AZD5438 potently inhibits the kinase activity of cyclin E-cdk2, cyclin A-cdk2, cyclin B1-cdk1, p25-cdk5, […]