LookPharma – Page 676 – Look Pharma Limited

JTC-801

Feb 23, 2018adminActive small molecule, Products244218-51-7, JTC-801, JTC801

Cat No:LP000130 Product Name:JTC801 CAS No:244218-51-7 Purity: ≥99% Solubility: In DMSO Storage: -10°C JTC-801 inhibits [3H]-nociceptin binding to ORL1 receptor expressed in HeLa cells with an IC50 value of 94±8.6 nm at a [3H]-nociceptin concentration of 50 pM. JTC-801 weakly inhibits the binding of the ligands to human δ receptor (IC50>10 μM), κ receptor (IC50>10 μM), and μ […]

A-803467

Feb 23, 2018adminActive small molecule, Products944261-79-4, A-803467

Cat No:LP000129 Product Name:A-803467 CAS No:944261-79-4 Purity: ≥99% Solubility: In DMSO Storage: -10°C A 803467 is a selective Nav1.8 sodium channel blocker with an IC50 of 8 nM; over 100-fold more selective vs. human Nav1.2, 1.3, 1.5 and 1.7. IC50 value: 8 nM Target: Nav1.8 sodium channel A 803467 dose-dependently reduces behavioral responses in a […]