Dalcetrapib

Active small molecule, Products, , ,

Cat No:LP0000138 Product Name:Dalcetrapib;JTT705;RO4607381 CAS No:211513-37-0 Purity: ≥99% Solubility: In DMSO Storage: -10°C Dalcetrapib (JTT-705; RO-4607381) is a rhCETP inhibitor with IC50 of 0.2 μM that increases the plasma HDL cholesterol. IC50 value: 0.2 uM [1] Target: CETP in vitro: Dalcetrapib modulates CETP activity. Dalcetrapib induces a conformational change in CETP, when added to human […]

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HQL-79

Active small molecule, Products,

Cat No:LP000137 Product Name:HQL-79 CAS No:162641-16-9 Purity: ≥99% Solubility: In DMSO Storage: -10°C HQL-79 is a selective inhibitor of hematopoietic prostaglandin D (PGD) synthase. Structurally, it is a synthetic tetrazole compound originally prepared as a possible antihistamine.1 Subsequent evaluation in models of allergy and asthma demonstrates the HQL-79 is orally available, and inhibits the synthesis […]

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