Cat No:LP000144 Product Name:GNF-2 CAS No:778270-11-4 Purity: ≥99% Solubility: In DMSO Storage: -10°C GNF-2 is a highly selective non-ATP competitive inhibitor of oncogenic Bcr-Abl activity (IC50 = 0.14 μM). IC50 value: 0.14 uM [1] Target: Bcr-Abl in vitro: Ba/F3 cells harboring native or T315I mutated Bcr-Abl constructs were treated with GNF-2 and AKIs. We monitored […]
Cat No:LP000143 Product Name:IOX2 CAS No:931398-72-0 Purity: ≥99% Solubility: In DMSO Storage: -10°C IOX2 is at least 2-5000 fold selective, as judged by IC50 values, for PHD2 over the KDMs and Factor Inhibiting HIF(FIH)[1]. IOX2 significantly upregulates the transcription of VEGF-A and BNIP3 in normal human epidermal keratinocytes (NHEK) and normal human dermal fibroblasts (NHDF) […]