AT-406

Active small molecule, Products, ,

Cat No:LP000148 Product Name:AT-406;SM-406 CAS No:1071992-99-8 Purity: ≥99% Solubility: In DMSO Storage: -10°C AT-406 is an orally bioavailable Smac/DIABLO mimetic and antagonist of the inhibitor of apoptosis proteins (IAPs). It binds to XIAP, cIAP1, and cIAP2 proteins with Ki values of 66.4, 1.9, and 5.1 nM, respectively.1 It has been shown to inhibit cancer cell […]

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R406

Active small molecule, Products,

Cat No:LP000147 Product Name:R406 CAS No:841290-80-0 Purity: ≥99% Solubility: In DMSO Storage: -10°C R406 is a potent Syk inhibitor with IC50 of 41 nM, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. IC50 value: 41 nM [1] Target: Syk in vitro: R406 is a potent inhibitor of immunoglobulin E (IgE)- and IgG-mediated […]

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