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D-6413

Feb 24, 2018adminActive small molecule, Products74588-78-6, D-6413

Cat No:LP000164 Product Name:D-6413 CAS No:74588-78-6 Purity: ≥99% Solubility: In DMSO Storage: -10°C D-64131 is a novel inhibitor of Tubulin polymerization that competitively binds with [(3)H]colchicine to αβ-Tubulin. IC50 Value: N/A Target: Microtubule/Tubulin in vitro: D-64131 is cytotoxic and inhibits tumor cell proliferation in vitro (IC50 = 74 nM). D-64131 prevents growth of tumor models […]

AG-490

Feb 24, 2018adminActive small molecule, Products134036-52-5, AG-490

Cat No:LP000163 Product Name:AG-490 CAS No:134036-52-5 Purity: ≥99% Solubility: In DMSO Storage: -10°C A tyrosine kinase inhibitor with potent activity against EGFR, STAT3, JAK3/STAT, JAK3/AP-1 and JAK3/MAPK. Suppresses IL-2 signaling pathway, inhibits T-cell growth and activation of JAK3, AP-1, STAT, MAPK. Has anti-proliferative and anti-invasive effect on cancer cells.