LY-364947（HTS466284）

Active small molecule, Products,

Cat No:LP000176 Product Name:LY-364947;HTS466284 CAS No:396129-53-6 Purity: ≥99% Solubility: In DMSO Storage: -10°C LY-364947 is an ATP competitive and tight-binding inhibitor, inhibiting phosphorylation of P-Smad3 by TGFβR-I Kinase with Ki of 28 nM. LY-364947 inhibits in vivo Smad2 phosphorylation within the NMuMg cells with IC50 of 135 nM. LY-364947 reverses TGF-β-mediated growth inhibition in NMuMg […]

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GW7647

Active small molecule, Products,

Cat No:LP000175 Product Name:GW7647 CAS No:265129-71-3 Purity: ≥99% Solubility: In DMSO Storage: -10°C GW7647 (1 μM) causes a significant increase of PDZK1 protein expression to 129.7 ± 6.5% of vehicle treated control in Caco2BBE cells in the absence and presence of IL-1β. GW7647 also attenuates the IL-1β-mediated decrease in PDZK1 expression[1]. GW7647 (50 nM) stimulates […]

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