PF-8380

Active small molecule, Products,

Cat No:LP000180 Product Name:PF-8380 CAS No:1144035-53-9 Purity: ≥99% Solubility: In DMSO Storage: -10°C PF-8380 also inhibits rat autotaxin with an IC50 of 1.16 nM with FS-3 substrate. Potency of PF-8380 is maintained when using enzyme produced from fetal fibroblasts used in combination with lysophosphatidyl choline (LPC) as a substrate. In human whole blood incubated with […]

READ MORE

ZM 306416（CB 676475）

Active small molecule, Products, ,

Cat No:LP000179 Product Name:ZM 306416;CB 676475 CAS No:690206-97-4 Purity: ≥99% Solubility: In DMSO Storage: -10°C ZM-306416 selective anti-proliferative effect toward the EGFR addicted NSCLC cell lines H3255 and HCC4011 (IC50=0.09±0.007 μM and 0.072±0.001 μM respectively), while sparing the wild type EGFR cell lines A549 and H2030 (IC50>10 μM). ZM-306416 is also found to inhibit the […]

READ MORE