Cat No:LP000190 Product Name:HA14-1 CAS No:65673-63-4 Purity: ≥99% Solubility: In DMSO Storage: -10°C HA14-1 is a nonpeptidic ligand of a Bcl-2 surface pocket. HA14-1 induces the activation of Apaf-1 and caspases, possibly by binding to Bcl-2 protein and inhibiting its function. The interaction of HA14-1 with the Bcl-2 surface pocket appeared to be specific for […]
Cat No:LP000189 Product Name:Apoptosis Activator 2 CAS No:79183-19-0 Purity: ≥99% Solubility: In DMSO Storage: -10°C Apoptosis Activator 2 is a potent apoptosis activator; increases procaspase-9 processing and subsequent caspase-3 activation. IC50 value: 4-9 uM(Leukemia origin cells)[1] Target: Apoptosis activator in vitro: Apoptosis Activator 2 promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome. […]