Varespladib(LY315920)

Cat No:LP000194 Product Name:LY315920 CAS No:172732-68-2 Purity: ≥99% Solubility: In DMSO Storage: -10°C LY315920 (Varespladib) is a potent and selective human non-pancreatic secretory phospholipase A2 (sPLA) inhibitor with IC50 of 7 nM. IC50 value: 7 nM Target: sPLA2 in vitro: LY315920 exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including […]

TWS119

Cat No:LP000193 Product Name:TWS119 CAS No:601514-19-6 Purity: ≥99% Solubility: In DMSO Storage: -10°C TWS119 induces neuronal differentiation in P19 EC cells and primary mouse ESCs. TWS119 binds to GSK-3β with KD of 126 nM, and modulates the activity of the complex, triggering downstream transcriptional events that lead the neuronal induction[1]. TWS119 (< 4 μM) significantly […]