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LY500307(Erteberel)

Feb 25, 2018adminActive small molecule, Products533884-09-2, Erteberel, LY500307

Cat No:LP000198 Product Name:LY50030;Erteberel CAS No:533884-09-2 Purity: ≥99% Solubility: In DMSO Storage: -10°C Erteberel is a potent and selective agonist of estrogen receptor β (ERβ; Ki = 1.54 nM; EC50 = 3.61 nM).1 Erteberel reduces the viability of patient-derived, ERβ+ primary glioblastoma (GBM) cells, significantly reducing in vitro colony formation and inducing apoptosis.2 It induces […]

LY2940680(Taladegib)

Cat No:LP000197 Product Name:LY2940680 CAS No:1258861-20-9 Purity: ≥99% Solubility: In DMSO Storage: -10°C Smoothened (Smo) is a GPCR-like receptor that, with Patched, mediates hedgehog (Hh) signaling to regulate gene expression through the Gli transcription factors.1 LY2940680 is an antitumor agent that binds to the human Smo receptor and inhibits Sonic Hh-induced Gli1 expression (IC50 = […]