Panobinostat

Active small molecule, Products, , ,

Cat No:LP000210 Product Name:IBH589 CAS No:404950-80-7 Purity: ≥99% Solubility: In DMSO Storage: -10°C Panobinosta (LBH589) induces apoptosis of both MOLT-4 and Reh cells in a time- and dose-dependent manner. Panobinosta treatment results in histone (H3K9 and H4K8) hyperacetylation and regulation of cell-cycle control genes in Reh cells[1]. Panobinostat exhibites potent antiproliferative activity in human NSCLC […]

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AZD5363(Capivasertib)

Active small molecule, Products,

Cat No:LP000209 Product Name:AZD5363;Capivasertib CAS No:1143532-39-1 Purity: ≥98% Solubility: In DMSO Storage: -10°C AZD5363, a novel pyrrolopyrimidine-derived compound, inhibits all AKT isoforms with a potency of 10 nM or less and inhibits phosphorylation of AKT substrates in cells with a potency of approximately 0.3 to 0.8 μM. AZD5363 inhibits phosphorylation of these substrates with an […]

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