Cat No:LP000224 Product Name:SU11274;PKI-SU11274 CAS No:658084-23-2 Purity: ≥99% Solubility: In DMSO Storage: -10°C SU11274 exhibits greater than 50-fold selectivity for Met versus Flk and more than 500 times selectivity versus other tyrosine kinases such as FGFR-1, c-src, PDGFbR, and EGFR. SU11274 inhibits the phosphorylation of key regulators of the PI3K pathway, including AKT, FKHR, or […]
Cat No:LP000223 Product Name:QNZ,EVP4593 CAS No:545380-34-5 Purity: ≥99% Solubility: In DMSO Storage: -10°C QNZ (Compound 11q) has a suppressing effect of the NF-κB mediated-inflammatory response. QNZ inhibits edema formation dose-dependently[1]. QNZ (EVP4593) reduces the number of lysosomes/autophagosomes and store-operated channel (SOC) currents in Huntington’s disease (HD). Normalization of calcium transport within neurons in response to […]