Catalog No:LP000236 Product Name:PD173074 CAS No: 219580-11-7 Purity: ≥99% Solubility: In DMSO Storage: -10°C PD 173074 inhibits autophosphorylation of FGFR1 in a dose-dependent manner with an IC50 in the range 1-5 nM. PD 173074 is an ATP-competitive inhibitor of FGFR1 with an inhibitory constant (Ki) of 40 nM[1]. PD 173074 and SU 5402 produce concentration-dependent […]
Cat No:LP000235 Product Name:XL-147,SAR245408,pilaralisib CAS No: 934526-89-3 Purity: ≥99% Solubility: In DMSO Storage: -10°C In assays performed using purified proteins in a luciferase-coupled chemiluminescence format, XL147 displays potent inhibitory activity against Class I PI3K isoforms p110α, p110δ, and p110γ, with IC50s of 39, 36, and 23 nM, respectively. XL147 is less potent against the remaining […]